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BAX antibody (AA 41-76)

This Rabbit Polyclonal antibody specifically detects BAX in WB, IHC and FACS. It exhibits reactivity toward Human.
Catalog No. ABIN2797999

Quick Overview for BAX antibody (AA 41-76) (ABIN2797999)

Target

See all BAX Antibodies
BAX (BCL2-Associated X Protein (BAX))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This BAX antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Binding Specificity

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    AA 41-76

    Purpose

    Rabbit Anti-Human Bax (BH3 Domain Specific) Antibody

    Immunogen

    This Bax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-76 amino acids from human Bax.

    Isotype

    Ig Fraction
  • Application Notes

    Western Blot, Immunohistochemistry, Flow Cytometry
    Recommended Dilutions
    WB: 1:1000, IHC: 1:50-100, FC: 1:10-50Bax Antibody(BH3) with the Bax gene.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.600 mg/mL

    Storage

    4 °C,-20 °C

    Storage Comment

    2-8°C (short-term), -20°C (long-term)
  • Target

    BAX (BCL2-Associated X Protein (BAX))

    Alternative Name

    Bax

    Background

    Target Description: Bax belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bax forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of the Bax gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

    Gene Symbol: BAX

    Molecular Weight

    21184 Da

    Gene ID

    581

    UniProt

    Q07812

    Pathways

    p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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